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Lock and Key of Medicine

Monoclonal Antibodies and the Transformation of Healthcare
by Lara V. Marks
Yale Univ Pr

List price $40.00 / Sale price $7.99
Your net price $3.99
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Pub Date: 2015
Format: Hardback with bw illus.
Pages: 316 pp.
Size: 6.25 x 9.50 inches

ISBN: 9780300167733
TB Code: 1805449
Availability: 124 in stock

This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world’s top ten blockbuster drugs and make up a third of new introduced treatments.